Gunpowder Heart is a story about Claudia and Maria, who roam the streets of the city of Guatemala. Claudia, who works at a call center, is uninterested in the world around her and lives with her activist grandfather who tries to persuade her to join his cause. On the other hand, Maria is more spontaneous and lives with her mother in the outskirts of the city.
The chaotic streets are filled with common stories of abuse, unforgiving police officers, and charming secret corners. However, everything changes one night when Claudia and Maria are attacked by three men. Although they manage to escape, Claudia is faced with the dilemma of choosing revenge or listening to her grandfather's advice.