Zoe Hart is a recent medical-school graduate who works tirelessly to be the best doctor she can be. But during her residency in New York she doesn't get the fellowship she wants, she is told she needs to treat her patients as people, and is advised to do some GP work.
It turns out that a doctor from Alabama saw her at her graduation and asked her to join his practice and he's been sending letters asking her to join his practice. But when she arrives she learns that the man died and bequeathed his practice to her. But his partner had been hoping to be the sole doctor in town, so is not welcoming her with open arms, and the man's daughter is nasty to her.
Zoe is about to leave when she learns why the man was interested in her and decides to stick it out.