Dave is a loser who hasn't held any job for very long, though he claims to have helped build houses after Hurricane Katrina. He moves from place to place, and his sensible brother Jim has finally found him in a wigwam on an Indian reservation in South Dakota. Jim had to find Dave because their father ("The Colonel") died. So they go back to Kansas City for the funeral.
Dinner with the family is awkward and unpleasant. What the brothers did should never happen on such a solemn occasion. But once they finish with the funeral, the brothers have to claim their inheritance, which includes a cabin on the lake near Branson, Missouri. Can you say road trip?
The brothers don't get along all that well. Jim went to college and has a job and a family, and Dave doesn't seem to care about much other than having a good time. And when they finally arrive at the cabin, it's a dump. Should they just tear it down, sell the property and split the money? Although there is a lot of great memorabilia, and a huge sports card collection. Dave's main interest is his Alonzo Mourning rookie card.
Before they decide to do anything, the brothers have to meet with The Colonel's business partner Jon Charbineau, who is quite a character and looks like a relic from a 70s action TV series. Well, at least he's not wearing a polyester leisure suit. His clothes actually look normal. It's just his face, hair, and sunglasses. There is money, and there are coupons for Branson attractions. The brothers ... well, Dave ... takes full advantage of the chance to enjoy this tacky tourist mecca. The cabin is too much of a dump so they rent a motel room from another guy who pranks the brothers good. It might have worked except no one else is in sight.
Dave has a great scene when he tries--in a bathrobe--to eat from a fancy hotel's buffet when he's not even a guest. He manages to break the law enough times that the brothers meet Sheriff Wegman and Deputy Bruce, who play "good cop, bad cop".
As the brothers decide to fix up the cabin, they have a number of adventures and meet interesting people. Lauren is a nice normal girl who used to date Jim. Petra is a beautiful and friendly immigrant waitress who might be a hooker.