In an attempt to get over a serious case of cold feet, Backpackers finds a recently engaged Ryan (Noah Reid, Titanic) and Beth (Meghan Heffern, Almost Heroes) embarking on separate European adventures ahead of their wedding. While traveling, they are free to act alone, adopting the mantra "what happens in Europe, stays in Europe." But hours after Ryan's affair with his party animal and his womanizing best friend Brandon (Dillon Casey, Nikita), he realizes he's made a big mistake and sets off on the quest. of the. The only problem is that he has no idea where he might be, they never exchanged itineraries. This marks the beginning of a wild adventure that takes the duo to the Amalfi Coast, Rome, Berlin, Prague, and Paris as they search for Beth, try to avoid an annoying Australian, fend off a homicidal maniac, and fit in some action. in the path. .