The entire game is a "What If?" scenario where Frank West covered the Fortune City outbreak, instead of Chuck Greene. After surviving the outbreak that occurred in Dead Rising, Frank West quickly became a bit of a celebrity. After authoring a successful book, he is given his own talk show, but soon wastes his opportunities and money as his fifteen minutes of fame expire. In hopes to regain a place in the spotlight, he accepts an offer from Tyrone King to appear as a special guest on Terror is Reality