"Honeymoon for One" tells the story of Eve Parker (Sheridan), a driven and successful advertising executive from Los Angeles. She is devastated when she discovers that her fiancé Greg (Baladi) has been cheating on her. Leaving Greg behind, Eve decides to go on their honeymoon alone, to a breathtaking castle in the Irish countryside that Greg's company has just bought and plans to turn into a golf course.
However, Eve soon realizes that staying in the honeymoon suite isn't as sweet as she had hoped. Everything starts to go wrong, from her lost luggage to her repeated run-ins with the estate's manager Sean (Wise), a handsome outdoorsman who seems to always get on her nerves. A culture clash ensues between this big-city girl and the nature-loving Irishman, but soon Sean sweeps Eve off her feet.
Just as Eve is starting to trade in her high heels for hiking boots, Greg shows up and threatens to turn Sean's beloved land into the 18th hole. He also tries to charm Eve back to the altar. Now, it will take more than just a little luck o' the Irish to save this honeymoon from going haywire.