Rushi is a story of a group of medical students with aspirations to become excellent doctors and serve humanity. Having obtained a spot at the prestigious Mamata Medical College, the story portrays individuals united as friends, yet haunted by the hardships of a medical college; their daily get go, emotional crests and troughs, and sacrifices to achieve their goals. The plot thickens as Rushi, the film's protagonist, is forced to make a decision he might regret for the rest of his life.