Star Trek: Enterprise follows the story of Humans breaking away from the Vulcans after a century of dependence. The Vulcans, despite inventing warp drive and making first contact, have not explored space.
Luckily, an incident with the Tsuliban in the first episode propels the Enterprise, led by Captain Jonathan Archer, on its first warp speed voyage. Archer faces challenges in his quest for exploration, including battles with alien warships, encounters with superior beings, alternate universes, and time travel.
Despite lacking a transporter, Archer displays exemplary leadership and gains the loyalty of his crew: communications officer Hoshi, chief engineer Trip, armory officer Malcolm, ensign Travis, alien doctor Phlox, and Vulcan Sub Commander T'Pol, who is tasked with keeping an eye on the captain.