An ancient artifact called the Book of Babylon has been opened unleashing a curse on the world of biblical proportions. An FBI agent Michael Riley and his niece Faith must follow a series of clues in the form of dreams and in some cases, corpses, in order find the source of a series of mental and physical afflictions befalling the populous. Yet the closer the two come to the Book of Babylon, they soon discover that a paramilitary group is killing anyone standing in their way of utilizing the power of the book, and the ancient artifact may have a dark plan of its' own.