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New York-based Daniel Murphy (Michiel Huisman) wakes on a flight home to Ireland for his Mum's funeral to find elderly passenger Padraig Murphy (Jim Norton) has died in the next seat. To his surprise the lonely Padraig had just listed him as his next of kin. In a bid to persuade his autistic brother Louis (Samuel Bottomley) to return to New York with him, Daniel agrees to drive Padraig's remains across the length of Ireland, from Cork to Rathlin Island, to be buried with his brother. Hitching a ride in the passenger seat is funeral-home temp Mary (Niamh Algar), who is on a desperate mission to correct a drunken mistake. Meanwhile, the police realize Daniel has no business driving off with Padraig's body, and Daniel, Mary, and Louis find themselves the focus of a nationwide manhunt.
As they cross the country and the border, sparks ignite between Mary and Daniel. But when a long-buried family secret endangers the fragile truce between the brothers, Mary gets caught in the crossfire. With its uniquely Irish sense of humor, this is a heartwarming and bittersweet comedy-drama about family, grief, and finding home.