Gunsmith Cats is a story about Rally Vincent and Minnie May Hopkins, a pair of gun shop owners who also do bounty hunting to make ends meet. Their lives take a turn when a Bureau of Alcohol, Tobacco, Firearms agent approaches them, threatening to arrest them for their lack of a retail license and unpaid taxes unless they cooperate in a sting operation to break a gun running ring.
After an initial success, they find themselves facing new problems as the ring's leader brings in a merciless assassin to eliminate them. Now, Rally and Minnie must rely on their skills, allies, and a bit of luck to survive this crisis.