Instinct tells the story of a former CIA operative, Dr. Dylan Reinhart, who is drawn back into his old life when the NYPD seeks his help to stop a serial killer.
Dr. Dylan Reinhart, portrayed by Alan Cumming, is a renowned author and university professor who teaches psychopathic behavior to his students. His peaceful life is disrupted when top NYPD detective Lizzie Needham, played by Bojana Novakovic, asks for his assistance in capturing a serial murderer who is using Dylan's first book as a guide.
Despite their initial clashes, Dylan and Lizzie realize that they can make a great team if they trust their instincts when it comes to catching killers. The series is based on the James Patterson book.